Human Induced Pluripotent Stem Cells Retain Some Gene Expression Of Donor Cells

Saturday, September 19, 2009 - 00:28 in Biology & Nature

A team of researchers has developed a safe strategy for reprogramming cells to a pluripotent state without use of viral vectors or genomic insertions. Their studies reveal that these induced pluripotent stem cells (iPSCs) are very similar to human embryonic stem cells, yet maintain a "transcriptional signature."

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