Endothelin Receptor May Play Role In Sickle Cell Pain

Saturday, September 12, 2009 - 07:07 in Biology & Nature

Endothelin may play a role in the pain of sickle cell disease because of a change in the endothelin B receptor. The activated receptor releases endorphins to help alleviate pain. Males who experience repeated pain may not have as much of the receptor and therefore do not release as much of the endorphins.

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