Unlikely Genetic Suspect Implicated In Common Brain Defect
Wednesday, August 12, 2009 - 03:28
in Biology & Nature
A genetic search using patients and mouse models has uncovered an unlikely gene critically involved in Dandy-Walker malformation, a common birth defect which causes mental retardation, motor delays and sometimes autism. This newly discovered function of the gene, which is never expressed in the brain, reveals a previously unknown role of the skull in directing brain development.