Long-awaited Atomic Structure Of Well-known Enzyme Solved: Discovery Heralds New Approaches To Protein-engineered Biofuels
Wednesday, May 20, 2009 - 20:35
in Physics & Chemistry
Researchers have identified the structural underpinnings of AADase, a widely known enzyme that was described correctly 43 years ago. However, it lacked a complete structural explanation. The original electrostatic perturbation hypothesis did not have a definitive structural elucidation -- until now. Using X-ray crystallography, researchers provide the missing structure that explains the original hypothesis about microenvironmental control of enzyme reactions within the cell.