Could Genetics Improve Warfarin Dosing? New Research Says Yes -- Now For The Clinical Trial

A world wide team of researchers addressed one of the trickiest drugs to prescribe -- the blood-thinner warfarin. Each patient's optimal dose varies widely, is hard to predict, and is crucial for his or her safety. Using data from thousands of genetically and geographically diverse patients, the international team developed a gene-based dosing strategy that could work for a broad range of patients. To test the concept in patients, NIH is launching a large-scale clinical trial.

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