New Model For Nuclear Pore Complex Backed By Structural Study

Saturday, December 27, 2008 - 23:28 in Physics & Chemistry

In higher organisms, the genetic material is confined and protected in the cell nucleus. In order for a healthy cell to function, the DNA must send manufacturing orders through the double membrane of the nucleus and into the cell's cytoplasm, where the protein production factories are and where most cellular functions are carried out. The sole portals through which these instructions pass -- nuclear pore complexes -- have a say in what the orders are and how they are conveyed. But these conspicuously large structures have ironically proved all but inscrutable to researchers over the years.

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