Curbing Hormones' Effects In Obese Patients Could Aid Against Breast Cancer

Wednesday, December 3, 2008 - 14:21 in Health & Medicine

Results from cell culture studies suggest a class of anticancer compounds called EGFR inhibitors, largely written off for breast cancers, could be effective in obese patients. The hormones leptin and IGF-1 synergistically stimulate migration and invasion in breast cancer cells. EGFR inhibitors block this stimulation.

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