Tumor Suppressor Inhibits Cell Growth
Friday, August 8, 2008 - 13:28
in Biology & Nature
Researchers have described the mechanism by which p53 regulates cells and protects them against DNA damage that might lead to cancer. The study shows that two p53 target genes -- called Sestrin1 and Sestrin2 -- provide an important link between p53 and a protein kinase called mTOR, a central regulator of cell growth.