Wealth Of Genomic Hotspots Discovered In Embryonic Stem Cells

Singapore scientists unveil an atlas showing the location of "genomic hotspots" of essential protein "switches" (transcription factors) that help maintain the embryonic stem cell state. Using advanced high throughput sequencing technology, the scientists discovered over 3,000 hotspots. These findings could improve understanding of the unique properties of stem cells that enable them to maintain their intriguing ability to grow and differentiate to virtually any cell type.

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