Seeing Alzheimer's Amyloids With Electron Microscopy For First Time

Monday, May 12, 2008 - 17:28 in Biology & Nature

In an important step toward demystifying the role protein clumps play in the development of neurodegenerative disease, researchers have created a stunning three-dimensional picture of an Alzheimer's peptide aggregate using electron microscopy. Researchers have shown -- for the first time -- how A-beta peptide, found in the brains of Alzheimer's patients, forms a spaghetti-like protein mass called an amyloid fibril.

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