Fruit Fly Avoidance Mechanism Could Lead To New Ways To Control Pain In Humans

Sunday, May 11, 2008 - 19:21 in Biology & Nature

At first, fruit flies eat like horses. Hatching inside over-ripe fruit where they were laid, they feed wildly in the sugar-rich environment until nature sends them an offer they can't refuse. To survive, they must leave the fruit, wander off and burrow into the earth where they avoid food as if it were poison. Only then can the larvae grow and hatch into flies that will take wing to lay their own eggs. Researchers have now discovered that the important developmental switch from food attraction to aversion in the fruit fly larva is controlled by a timing mechanism in the brain and its sensory system. The study shows how this important avoidance mechanism has been recruited into evolutionary processes to promote development and could lead to new methods of controlling pain in humans and other animals.

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