Glowing Zebrafish Help Researchers Track Role Of Sugars In The Cell

The transparent embryos of zebrafish are popular models of development, and scientists routinely tag proteins with tracers to study protein trafficking in the embryo. Sugars, which decorate 90 percent of the proteins on a cell's surface, have been harder to track. Now, UC Berkeley scientists have developed a way to attach fluorophores to sugars and follow their changing patterns throughout early development, providing a tool that could reveal the true role of cell-surface sugars.

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