Single gene defect causes brain tumour

Pilocytic astrocytoma, the most common brain tumour in children, is usually slow-growing and benign. However, surgeons often cannot completely remove the diffusely growing tumour. This means that patients need further treatment in order to destroy remaining tumour tissue. Chemotherapy or radiation therapy can lead to severe side-effects and have only little effect on these slowly growing tumours. Affected children therefore urgently need new, targeted therapies...

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