IL28B gene predicts treatment outcome for liver transplantation patients
Thursday, March 3, 2011 - 08:20
in Health & Medicine
German researchers have found a significant association of IL28B genotypes to interferon-based antiviral treatment outcome, and to graft inflammation caused by hepatitis C virus (HCV). The study determined that the presence of G-allele serves as a marker for severe HCV-induced graft inflammation, as well as a predictor for unsuccessful treatment. Study findings - the largest to report on the role IL28B variants in a transplant cohort with recurrent HCV - are published in the March issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases...