Tumour suppressor APC could stop cancer through its effect on actin cytoskeleton

Tuesday, June 22, 2010 - 05:11 in Biology & Nature

The APC protein serves as the colon's guardian, keeping tumours at bay. Now researchers reveal a new function for the protein: helping to renovate the cytoskeleton by triggering actin assembly. The result suggests a second way that mutations in APC could lead to cancer. The study appears online on June 21 in the Journal of Cell Biology (www.jcb.org)...

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