Solid-pseudopapillary neoplasm of the pancreas or pancreatic endocrine tumour?
Thursday, March 18, 2010 - 08:52
in Health & Medicine
Solid-pseudopapillary neoplasm (SPN) of the pancreas is relatively rare. There are some similarities between SPN and pancreatic endocrine tumour (PET), especially the non-functioning ones, in clinical and pathological manifestations. Even the results of immunohistochemistry reported in the literature showed that the expression profiles of the two tumours overlapped, which sometimes results in difficulty distinguishing the two entities. In recent years, studies have shown that the vast majority of SPN harbour a point mutation on exon 3 of beta-catenin gene, which has not yet been discovered in other pancreas tumours...