Gladstone scientists identify key protein in energy regulation

Wednesday, March 17, 2010 - 09:01 in Biology & Nature

With obesity and obesity-related diseases epidemic in the developed world, a clear understanding of how metabolism is regulated is crucial. One of the key metabolic pathways involves the oxidation of fat. In the current edition of the journal Nature, scientists at the Gladstone Institute of Virology and Immunology report on a new mechanism that governs this pathway and in the process identified a novel potential therapeutic target for controlling fat metabolism. The target is a protein from the mitochondria, or the 'power plants' of every cell that are responsible for processing oxygen and converting substances from the foods we eat into energy for essential cell functions...

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