Cell-cell interactions adapt to the stiffness of the environment

The ability of tissue cells to stick to one another is critical for many physiological and pathological processes. But normal living cells need to do much more than just hold on tight, they must monitor their environment and respond with appropriate changes in shape, migration, and proliferation. Now, a new study published online on February 16th by Cell Press in the Biophysical Journal provides intriguing insight into how mechanical interaction with the external environment influences cell shape and the forces generated by a cell's internal 'skeleton'...

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