New layer of control over human embryonic stem cells found

Friday, May 1, 2009 - 10:42 in Biology & Nature

Researchers have discovered an added layer of complexity in the network that determines human embryonic stem cell fate. A report publishing online 30th April in the journal Cell, a Cell Press publication, shows that a microRNA known as miR-145 lowers the activity of three key ingredients in the 'recipe' for making embryonic stem cells. The discovery may have implications for improving the efficiency of methods designed to reprogram differentiated cells into embryonic stem cell-like cells and for the use of those transformed cells in replacing cells lost to disease or injury, the researchers said...

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