Diminuendo - new mouse model for understanding cause of progressive hearing loss
Monday, April 27, 2009 - 08:35
in Biology & Nature
Scientists of Helmholtz Zentrum Muenchen, led by Professor Martin Hrabe de Angelis, director of the Institute of Experimental Genetics, have developed a new mouse model with a genetic mutant in which a single base of a specific microRNA seed region has been altered. Mice carrying this miR-96 mutation suffer progressive hearing loss as they get older. Moreover, if they carry two of these mutants, their sensory hair cells are impaired from birth on...
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