May supplementation of docosahexaenoic acid suppress colon tumour cell growth?

Monday, March 9, 2009 - 10:08 in Health & Medicine

Colon cancer is one of the leading causes of death in Western countries. The role of n-3 and n-6 PUFAs in colorectal carcinoma cell growth has not been well studied. It is known that PGE2, generated from AA, is an important factor in the tumourigenesis of colorectal cancer. However, previous in vitro observations have led to uncertainty regarding a differential role of n-3 and n-6 PUFA for growth of tumour cells, as some findings are contradictory, and most studies have not addressed the effect of a changed n-3/n-6 PUFA ratio on cell proliferation...

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