Magnetic nanoparticles navigate therapeutic genes through the body

Thursday, March 5, 2009 - 14:28 in Biology & Nature

Scientists of the national German metrology institute, the Physikalisch-Technische Bundesanstalt (PTB), have developed a highly sensitive measuring method with which the efficiency of gene transfer in cases if cardiovascular diseases can be investigated. The researchers determine, accurate to the picogram per cell, the quantity of magnetic particles that are situated on the gene - and thus also the quantity of the therapeutically effective genes or cells. In a joint study with the University of Bonn it became clear: By means of the magnetic method it is possible to dramatically increase the efficiency of the gene transfer in comparison to the non-magnetic method...

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