Compound LJ001 Acts Like Antibiotic Against Viruses
Unlike antibiotics, which kill many different types of bacteria, antiviral drugs for the most part need to target individual, specific viruses. A drug that attacks a multitude of viruses -- an antibiotic for viruses, effectively -- would be a significant boon for medicine. And a group of researchers led by UCLA scientists just may have discovered exactly that. Writing in Proceedings of the National Academy of Sciences, the researchers describe an early proof-of-concept study on a chemical they call LJ001. The chemical attacks the structure of viruses themselves, and may potentially cure a wide swath of disease ranging from influenza to AIDS to Ebola. For all the complexity of the diseases they cause, viruses are very simple; just a bunch of DNA in a lipid sack. LJ001 attacks that lipid sack, as well as the lipid membrane of healthy cells. But whereas the healthy cells can easily repair the damage,...