New CRISPR-Cas9 variants can respond to viral proteases
Thursday, January 10, 2019 - 11:30
in Biology & Nature
Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of Cas9-fusion proteins for diverse applications beyond simple DNA cutting, such as base editing and epigenetic modifications. The work appears January 10 in the journal Cell.