Chemists synthesize molecular pretzels

Friday, May 26, 2017 - 06:11 in Physics & Chemistry

Chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have discovered a new class of molecules. This week they report in Nature Communications on their synthesis method leading to 'quasi[1]catenanes': pretzel-like molecules consisting of two molecular rings 'oppositely' coupled at a central carbon atom. The discovery is an important step towards synthesis of lasso peptides; new molecules with a potential use as medicines.

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