Going with the flow: Facile synthesis of a complex biologically active oligopeptide
Thursday, December 8, 2016 - 10:01
in Physics & Chemistry
Scientists at the Tokyo Institute of Technology utilized micro-flow amide bond formation to achieve total synthesis of the structurally complex, biologically active natural product, feglymycin. The technique they developed allows for efficient preparation of requisite oligopeptides containing highly racemizable amino acids and could directly impact how these agents will be synthesized in the future.