Towards therapeutic applications of mRNA—new insights into translation and decapping

Thursday, December 1, 2016 - 06:31 in Biology & Nature

Gene therapy gives hope to millions of patients. Researchers from the University of Warsaw have been working on mRNA containing a modified fragment that initiates protein biosynthesis. Recently published results reveal that new compounds designed and synthesized at the University of Warsaw are more stable and effective than their natural equivalents, and their synthesis is simpler. The compounds lend a better understanding of the mechanisms of protein biosynthesis in cells, which in turn could lead to better therapeutics.

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