Scientists reveal how signals from pathogenic bacteria reach danger sensors of cells

Thursday, September 29, 2016 - 05:31 in Health & Medicine

Researchers at St. Jude Children's Research Hospital have discovered the way signals from infectious bacteria gain entry into the cytoplasm of host cells to activate disease-fighting inflammasomes. Inflammasomes are protein machines in the cell that serve as "danger sensors" for infection and which set in motion rapid immune defenses against pathogens. The findings appear online today in the journal Cell.

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