A practical synthesis for benzazetidine compounds

Thursday, August 18, 2016 - 08:01 in Health & Medicine

(Phys.org)—A key chemical component to antibiotics, such as penicillin is the beta-lactam, a four-membered amide ring that is fused to another heterocycle. Researchers in drug design would like to explore compounds using a similar structure. One avenue may be found in the four-member azetidine ring. Similar to the beta-lactam ring, it is a four-membered amine heterocycle. However, less progress has been made for benzazetidines, an azetidine fused to a benzene ring, due to the significant ring strain in these four-membered scaffolds.

Read the whole article on Physorg

More from Physorg

Latest Science Newsletter

Get the latest and most popular science news articles of the week in your Inbox! It's free!

Check out our next project, Biology.Net