Cytochrome P450 synthetic analogs are temperature-dependent valence tautomers
Friday, June 24, 2016 - 04:21
in Health & Medicine
Cytochrome P450 is a well-known family of enzymes that are involved in drug metabolism. The active site contains a heme chemical structure in which an iron atom is bound to the heme cofactor within the enzyme. The oxidation state of the iron plays a key role in catalysis, notably in oxidizing organic compounds using O2, and an iron-sulfur bond is a key component to the enzyme's function.