CLIP-170 microtuble found to bind tightly to formins to accelerate actin filament elongation
Friday, May 20, 2016 - 08:00
in Physics & Chemistry
(Phys.org)—A team of researchers at Brandeis University in Massachusetts, has found that the CLIP-170 microtuble found in cells, which had been known to be important in cytoskeleton development, binds tightly to formins to accelerate actin filament elongation. In their paper published in the journal Science, the team describes their experiments with adding a fluorescent protein to the microtubule to better understand the roll CLIP-170 plays in actin flament assembly. In a Perspective piece on the work done by the team, Klemens Rottner with Universität Braunschweig in Germany also explains the role played by microtubules and actin filaments in the development of the eukaryotic cytoskeleton (the material that holds the shape of cells.)