Trypanosomes evade detection by swapping coat proteins through chromosomal rearrangement
Thursday, May 5, 2016 - 13:21
in Biology & Nature
African trypanosomes establish deadly, chronic infections of trypanosomiasis in the bloodstream by using repetitive 70-bp regions in the genome to regularly change out the active coat protein gene. Galadriel Hovel-Miner and colleagues at Rockefeller University and George Washington University report this discovery and describe its role in the process that trypanosomes use to evade host antibodies on May 5, 2016 in PLOS Genetics.