Researchers massively edit the genome of pigs to turn them into perfect human organ donors

Thursday, October 8, 2015 - 10:00 in Paleontology & Archaeology

(Phys.org)—One benefit of the closeness between pigs and humans is the potential to be organ donors. There are however, just a few nagging uncertainties that still stand in the way. The big one, the possibility of porcine endogenous retroviruses (PERVs) getting reactivated inside the human organ recipient, is no longer the concern it once was. That comes thanks to the recent groundbreaking work of the one-man army of genetics, George Church, and his lab at Harvard. The latest news, just reported in Nature, is that the group was able to use CRISPR gene-editing techniques to inactivate 62 PERVs in pig embryos.

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