How cells defend themselves against antibiotics and cytostatic agents

ABC Transporters are proteins that are embedded in the cell membrane and facilitate the transport across cellular barriers not only of an almost unlimited variety of toxic substances, but also of substances that are essential for life. They also play a role in the development of antibiotic resistance. A research group at the Goethe University in Frankfurt am Main, in co-operation with American colleagues, has now succeeded in elucidating the detailed structure of this transporter.

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