Chaperone protein subverts removal of glaucoma-causing protein
Tuesday, October 9, 2012 - 11:31
in Biology & Nature
The chaperone protein Grp94 can interfere with the clearance of another protein known to cause the glaucoma when mutated, a new study led by researchers at the University of South Florida has found. Using a cell model, the researchers also demonstrated that a new specific inhibitor of Grp94 facilitates clearance of the genetically-defective protein, called myocilin, from cells.