Control of gene expression: Histone occupancy in your genome

Monday, April 30, 2012 - 16:30 in Biology & Nature

When stretched out, the genome of a single human cell can reach six feet. To package it all into a tiny nucleus, the DNA strand is tightly wrapped around a core of histone proteins in repeating units—each unit known as a nucleosome. To allow access for the gene expression machinery the nucleosomes must open up and regroup when the process is complete.

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