Biosensors: Hormonal attractions

Monday, March 28, 2011 - 09:00 in Biology & Nature

Estrogen receptor (ER) proteins play a major role in controlling the transcription of genetic information from DNA to messenger RNA in cells. Understanding how ER proteins interact with specific DNA regulatory sequences may shed new light on important physiological processes in the body, such as cell growth and differentiation, as well as the development and progression of breast cancer. Guo-Jun Zhang at the A*STAR Institute of Microelectronics and co-workers have now developed a detector that uses silicon nanowires (SiNWs) to evaluate these interactions.

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