Conserved kinase protects cells from endosomal traffic jam
Wednesday, March 9, 2011 - 10:00
in Biology & Nature
Some molecules have a single, highly specific function in physiology, while others have a much broader remit. Kinases in the IKK (inhibitor of nuclear factor κB (NF-κB) kinase) family are of the latter sort, playing a variety of roles in the immune system, cancer, and differentiation. Previous work with a related kinase, IKKε, in Drosophila has shown that this protein regulates the cytoskeleton and cell elongation in a number of contexts. It has yet to be shown, however, how it accomplishes this.