Dendritic cells as a new player in arteries and heart valves

(PhysOrg.com) -- In 1973, Ralph M. Steinman launched a new scientific discipline when he published his discovery of the dendritic cell, an odd-shaped player in the immune system. Since then, dendritic cells have proved to be critical sentinels on the lookout for foreign invaders, involved in early immune responses such as graft rejection, resistance to tumors and autoimmune diseases. Now it appears they need to be considered in research on arterial and heart function, too, according to new experiments to be published February 16 in The Journal of Experimental Medicine.

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