Genetic based human diseases are an ancient evolutionary legacy

Tomislav Domazet-Lošo and Diethard Tautz from the Max Planck Institute for Evolutionary Biology in Plön, Germany, have systematically analysed the time of emergence for a large number of genes - genes which can also initiate diseases. Their studies show for the first time that the majority of these genes were already in existence at the origin of the first cells. The search for further genes, particularly those which are involved in diseases caused by several genetic causes, is thus facilitated. Furthermore, the research results confirm that the basic interconnections are to be found in the function of genes - causing the onset of diseases - can also be found in model organisms (Molecular Biology and Evolution).

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