Variation of normal protein could be key to resistance to common cancer drug

Thursday, August 28, 2008 - 10:14 in Health & Medicine

Researchers at the Moores Cancer Center at the University of California, San Diego (UC SD) in La Jolla have found evidence explaining why a common chemotherapy drug, cisplatin, may not always work for every cancer patient. They have shown that when a variant version of a key protein that normally causes cell death is active, patients may be resistant to the cancer-killing drug.

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