NIST Trumps the Clumps: Making Biologic Drugs Safer
Wednesday, July 23, 2008 - 14:56
in Physics & Chemistry
Scientists at the National Institute of Standards and Technology have developed a technique to measure the formation of clumps of proteins in protein-based pharmaceuticals. This first systematic study clarifies the conditions under which scientists can be assured that their instruments are faithfully measuring the formation of protein aggregates, a major concern because of its impact on quality control and safety in biologic drug manufacturing.
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