Innate Lymphoid Cells (ILCs) form an essential line of defense against enteric bacteria
Wednesday, August 8, 2018 - 11:40
in Health & Medicine
Mice deficient in innate lymphoid cells are vulnerable to lethal infection by the bacterial pathogen Yersinia enterocolitica (YE), which causes some forms of food poisoning. Moreover, activation by a cytokine called LIGHT, which is a member of the tumor necrosis factor (TNF) superfamily, is necessary for ILCs to mount an anti-bacterial response.