Researchers Uncover a Role for HSP90 in Gene-Environment Interactions in Humans

Thursday, February 23, 2017 - 13:01 in Biology & Nature

Researchers at Whitehead Institute have now uncovered a role for the protein-folding chaperone HSP90 in humans, not only as a modifier of the effects of mutations, but as a mediator of the impact of the environment on the function of mutant proteins. And these effects of HSP90 can alter the course of human diseases.

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