On the Path to Age-Defying Therapies
Thursday, March 29, 2012 - 14:00
in Health & Medicine
The drug rapamycin extends lifespan in lab animals, yet it's linked to two hallmarks of diabetes. By teasing apart its activity, researchers at Whitehead Institute and the University of Pennsylvania have determined that inhibiting only the protein cluster known as mTORC1 prolongs life in mice without adversely affecting glucose tolerance or insulin sensitivity.