Short snippets of RNA called microRNAs help to keep embryonic stem cells in their stem cell state. Researchers now have discovered the gene circuitry that controls microRNAs in embryonic stem cells. Mapping the control circuitry of stem cells reveals how they maintain themselves or decide to differentiate, providing key clues for regenerative medicine and reprogramming of adult cells to a stem cell state. These maps also aid our understanding of human development and diseases such as cancer.
- Putting microRNAs on the stem cell mapThu, 7 Aug 2008, 12:37:18 EDT
- New layer of control over human embryonic stem cells foundThu, 30 Apr 2009, 13:16:30 EDT
- Human embryonic stem cells and reprogrammed cells virtually identicalThu, 5 Aug 2010, 12:30:18 EDT
- Embryonic pathway delivers stem cell traitsThu, 15 May 2008, 12:28:57 EDT
- Rethinking reprogramming: A new way to make stem cells Thu, 7 Apr 2011, 13:35:36 EDT