For two decades, scientists have been pursuing a potential new way to treat bacterial infections, using naturally occurring proteins known as antimicrobial peptides (AMPs) that kill bacteria by poking holes in their cell membranes. Now, MIT scientists have recorded the first real-time microscopic images showing the deadly effects of AMPs in live bacteria.Researchers led by MIT Professor Angela Belcher modified an existing, extremely sensitive technique known as high-speed atomic force microscopy (AFM) to allow them to image the bacteria in real time. Their method, described in the March 14 online edition of Nature Nanotechnology, represents the first way to study living cells using high-resolution images recorded in rapid succession.Using this type of high-speed AFM could allow scientists to study how cells respond to other drugs and to viral infection, says Belcher, the Germeshausen Professor of Materials Science and Engineering and Biological Engineering and a member of the Koch Institute for...
- New microscopy technique offers close-up, real-time view of cellular phenomenaSun, 14 Mar 2010, 14:30:30 EDT
- All wrapped up: K-State researcher's graphene cloak protects bacteria, leading to better imagesTue, 15 Mar 2011, 11:03:38 EDT
- Scientists produce best image yet of atoms moving in real timeWed, 17 Apr 2013, 14:35:44 EDT
- Sharper, deeper, fasterMon, 25 Jul 2011, 16:34:21 EDT
- UCLA researchers use new microscope to 'see' atoms for first timeTue, 4 May 2010, 9:56:36 EDT