New mechanisms of self-organization in living cells

Monday, November 23, 2015 - 18:40 in Biology & Nature

Location of topologically associated domains (TAD) in the cell nucleus is shown. Chromosome is a structure inside the cell nucleus that carries a large part of the genetic information and is responsible for its storage, transfer and implementation. Chromosome is formed from a very long DNA molecule - a double chain of a plurality of genes. Given that the diameter of the cell nucleus is usually around hundredth of a millimeter or even less, while the total length of DNA constituting human genome is about two meters, it is clear that DNA must be packaged very tightly.

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