Unpacking embryonic pluripotency
Monday, November 9, 2015 - 18:50
in Biology & Nature
Blastocysts in this study were immunostained to show pluripotency factor NANOG localised to the inner cell mass, primitive endoderm specifier GATA6, outer trophectoderm marker CDX2 and nuclei. Researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust- Medical Research Council Cambridge Stem Cell Institute at the University of Cambridge have identified factors that spark the formation of pluripotent cells. Their findings, published in Developmental Cell, shed light on human embryonic development and help research into cell reprogramming and assisted conception.