Study reveals key structure in telomerase enzyme, a target for cancer drugs

Monday, October 5, 2015 - 16:30 in Biology & Nature

New findings revealed a molecular "tug of war " that plays a key role in the proper functioning of the telomerase enzyme. Researchers at UC Santa Cruz have determined the structure of a key part of the enzyme telomerase, which is active in most cancers and enables cancer cells to proliferate indefinitely. The new findings, published October 5 in Nature Structural & Molecular Biology, reveal how the enzyme carries out a crucial function involved in protecting the ends of chromosomes.

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